Symptoms of TIA

Definite Probably Not Alarm symptoms (may require admission)
Slurring Dizziness Known AF; or high stroke risk
Clumsiness Confusion Recurrent TIAs; more than 2 in last 2 weeks
Tingling/numbness General weakness Patient on anticoagulant. May need brain scan
Visual disturbance ABCD2 score of 4 or more

Thanks to Practice Nurse 41 8

Post-MI Care in Primary Care

Patients with a history of myocardial infarction will need appropriate follow-up in primary care to manage risk factors as far as possible, provide patient education and ensure patients are on correct medication.

Patient education to reduce risks of further MIs is important. In particular, patients should be advised to increase their fruit and vegetable intake to at least 5 portions daily, reducing salt and fat intake, adopting a Mediterranean-style diet including consumption of oily fish. Additional supplements of beta carotene, vitamin C or E are not connected with improving outcomes and reducing cardiac risks. NICE guidelines recommend post-MI patients to consume at least 7g of omega-3 fatty acids per week (2-4 portions of oil fish). For patients unable to achieve this, 1g daily omega-3 ester (Omacor) can be prescribed for up to four years for patients who have had an MI in the previous 3 months. Patients should also be advised to reduce their alcohol consumption to low-moderate levels (less than 21 units per week for men and 14 for women).

Obesity needs to be monitored and managed, as this will not only reduce lipid levels as well as blood pressure but also other conditions such as diabetes.

Smoking cessation help should be offered if appropriate. Nicotine replacement therapy is not advised immediately after an MI, but in the long-term continuing to smoke is a serious risk factor.

All post-MI patients should be offered cardiac rehabilitation with an emphasis on exercise. NICE guidelines recommend moderate exercise for 20-30 minutes (enough to feel lightly breathless) five times per week. Brisk walking is ideal. Sexual activity poses no more risk of a further MI, than in a person who had not had an MI. Although when treating erectile dysfunction it is important to remember that PDE5 (phosphodiesterase 5) inhibitors should be avoided in patients using nicorandil, but can be considered in stable patients six months post-MI.

The optimum lipid target is a total cholesterol of <4mmol/l, LDL cholesterol of <2mmol.

A brief anxiety and depression assessment may be required – referring on to mental health services if necessary.

Air travel can be considered three weeks post-MI, and although the DVLA need not necessarily be notified, it is inadvisable to drive in the four weeks immediately post-MI.

Optimum prescribing for post-MI patients includes:

Daily aspirin (proven to reduce death rate by 25%). This is a lifelong treatment and is a first-line drug. Clopidogrel may be prescribed instead of aspirin if a patient has a well-documented hyper-sensitivity. Clopidogrel may be prescribed alongside aspirin for 12 months in patients with non-ST segment elevation acute coronary syndrome.

ACE inhibitors (particularly in patients with left ventricular dysfunction or heart failure), although current NICE guidelines recommend all patients post-MI should be prescribed ACE inhibitors, after checking renal function. If the patient develops a severe cough or oedema, this would need to be reassessed.

Beta-blockers are responsible for a reduction in mortality of up to 25%. New patients may need to be informed that beta blockers can cause lethargy, but this should resolve after a few weeks.

Statins help reduce lipid levels, and it has been found that after five years’ use they prevent further cardiovascular events in 10% of patients. Statins can be started after liver function and CK has been measured to determine the patient’s baseline, although raised liver enzymes should not necessarily rule out the patient from statin therapy. A statin may be augmented by ezetimibe to reduce LDL and total cholesterol.

A low HDL cholesterol (<1mmol/l) is of particular risk to patient with type II diabetes. Fibrates are effective at raising HDL cholesterol.

Particular attention needs to be paid to the patient’s blood pressure – for post-MI patients the target is <130/80mmHg. To achieve this the beta blocker dose may need to be increased or the patient may also require a diuretic or calcium channel blocker.

UK Guidance on Diet could save around 33,000 Lives annually

A study has found if people adhered to the recommended 5 portions of fruit and vegetables each day and reduced their daily intake of salt to 3.5g as well as their saturated fat intake to 3% of their daily energy intake, this could prevent around 33,000 deaths each year. It was calculated that 20,800 coronoary artery disease deaths, 5,876 stroke deaths, amd 6,481 cancer deaths could be prevented each year by following such guidance. Around 12,500 deaths would be in the 75 years and under category.

Scarborough P et al (2010) Modelling the impact of a healthy diet on cardiovascular disease and cancer mortality Journal of Epidemiology and Community Health. Doi:10.1136/jech.2010.114520

Solar UV and Cardiovascular Disease in Women

A study has found that women who had exposure to solar UV light were at reduced risk of developing cardiovascular disease. The study also found that exposure to non-solar UV light increased a woman’s overall risk of dying from cancer.

Yang, L. et al. (2011) Ultraviolet exposure and mortality among women in Sweden. Cancer Epidemiology, Biomarkers and Prevention. 20, 4, 683-690.

Early Menopause

This is menopause experienced before the age of 45. These patients are more at risk of health conditions associated with the menopause, such as CHS, CVA and osteoporosis if they don’t take HRT.

Early menopause can be caused by a variety of factors such as; viral infections, enzyme deficiencies, chromosome abnormalities such as fragile X syndrome, and Turner’s syndrome. It may also be caused by FSH receptor gene polymorphism and mutation of inhibin B. Other medical factors include hypothyroidism, type I diabetes, Crohn’s disease, SLE, rheumatoid arthritis, Addison’s disease and myasthenia gravis.

There are other factors of a secondary nature which include chemo/radiotherapy, or oophrectomy.

Assessment and diagnoses will require blood tests for FSH, if necessary two weeks apart if there is no calculable cycle, bloods for testosterone, prolactin (to exclude polycystic ovary syndrome) TSH, progesterone (for fertility). Chromosome analysis for fragile X syndrome may be required, also the assessment ought to include a BMI, BP and bone density scan.

Because women with early onset menopause are at greater risk of the associated conditions, it is essential that they are screened initially and also that these checks are made regularly. Patient education regarding reversible risks factors of these conditions is vital.

For early menopause, HRT or a combined contraceptive pill can be prescribed; particularly as contraception still needs to be considered.

Risk Factors for Osteoporosis

  • Smoking
  • Excessive alcohol intake
  • Sedentary lifestyle
  • Excessively low BMI (including due to anorexia)
  • Amenorrhoea
  • Family history of osteoporosis
  • Previous fracture
  • Maternal history of hip fracture
  • Early menopause (before 45)
  • Calcium or vitamin D deficiency
  • Age
  • Prolonged use of cortico steroids
  • White or oriental genotype
  • Conditions affecting digestion including Crohn’s disease, ulcerative colitis, coeliac disease, liver disease

Care of the Post-MI Patient in Primary Care

According to the British Heart Foundation (BHF) in 2006 about 1.3 million people in the UK have had an MI, about 4% of men and 2% of women. Because of their medical history, they will need following up in the primary care setting to help reduce the risk of further events; this is done by a combination of patient education, modification of diet and lifestyle as well as regular checks and medication or further interventions.

In primary care, the major risk factors will therefore be addressed; for example, smoking, obesity, diet, inactive lifestyle, hypertension, dyslipidaemia, poorly-controlled diabetes, as well as ensuring the recommended MI prophylactic medications are prescribed.

Many of these interventions are under QOF with points awarded for specific interventions (such as regular blood pressure checks, blood lipid checks, identification of depression, anxiety or related mental illness, as well as therapies such as ACE inhibitors, beta blockers, aspirin, or angiotensin receptor blockers). It is important for all primary care settings to have robust policies in place for the care of post-MI patients as not all standard therapies are covered by QOF.

Because many of the cardiovascular risk factors are reversible, there needs to be an emphasis on patient education and empowerment. This is the most effective intervention and yet, according to the BHF, less than 40% of post-MI patients have access to this. Primary care nurses are well-placed to provide this.