Clinical features differentiating COPD and asthma (NICE 2010)

COPD Asthma
Smoker or ex-smoker Nearly all Possibly
Symptoms under age 35 Rare Often
Chronic productive cough Rare Often
Breathlessness Persistent and progressive Variable
Night time waking with breathlessness and and/or wheeze Uncommon Common
Significant diurnal variation or day-to-day variability Uncommon Common

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